Beauty / ActiDeep™ /

PelliFeel

Botanical complex demonstrating downregulation of pro-inflammatory cytokines in LPS-stimulated keratinocytes. 
Anti-inflammatory activity.
Antibacterial support.

PelliFeel™ is a 100% natural-origin, plant-derived active ingredient designed for sensitive and acne-prone skin formulations.

Developed through ActiDeep™ low-temperature extraction, PelliFeel™ combines Rosa Centifolia flower extract and Nigella Sativa seed extract to support inflammatory cascade modulation and microbial equilibrium.

The selected Mediterranean botanicals are recognized for their antioxidant capacity and skin-soothing properties, contributing to improved cutaneous comfort and formulation performance in stress-prone skin conditions.

In vitro study — HaCaT (24h)

PelliFeel™ reduces TNFα gene expression by 36.5%

TNFα is a key inflammatory mediator. Its regulation supports skin balance and comfort.

–36.5%

PelliFeel™ reduces IL-1α gene expression by 30.5%

IL-1α is involved in inflammatory cascade activation and skin irritation.

–30.5%

PelliFeel™ reduces IL-6 gene expression by 41.1%

IL-6 plays a central role in inflammation and cellular stress response.

–41.1%

PelliFeel™ • APF—409—2

Technical Profile

INCI
Rosa Centifolia Flower Extract, Nigella Sativa Seed Extract
Origin
Mediterranean botanicals
Natural Origin
100% natural
Certification
COSMOS compliant
Recommended dosage
0.01% – 1%
Solubility
Oil soluble
Application
Sensitive skin, acne-prone skin, soothing care, microbiome-friendly formulations
Technology
ActiDeep™ low-temperature extraction

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